Which factor primarily affects the effectiveness of oxygenator membranes during perfusion?

The effectiveness of oxygenator membranes during perfusion is primarily influenced by the surface area of the membrane. A larger surface area allows for increased gas exchange between the blood and the oxygenator, facilitating a more efficient transfer of oxygen into the blood and the removal of carbon dioxide.

The design of oxygenator membranes typically incorporates a large surface area in order to maximize contact time and space for gas exchange. This is crucial in scenarios where the demand for oxygen is high, such as during open-heart surgeries or prolonged perfusion. Therefore, the surface area directly correlates with the oxygenation capacity and efficiency of the membrane.

While temperature, viscosity, and the type of blood can play supplemental roles in overall perfusion and gas exchange, the essential function of the membrane for effective oxygenation hinges largely on the available surface area.