Which drug causes vasodilation through beta-adrenergic actions and alpha-adrenergic blockage?

The drug that causes vasodilation through beta-adrenergic actions and alpha-adrenergic blockage is indeed phenothiazine. Phenothiazines are primarily known as antipsychotic medications, but they also possess significant cardiovascular effects. Specifically, they can block alpha-adrenergic receptors, leading to vasodilation, while simultaneously stimulating beta-adrenergic receptors, which results in the relaxation of vascular smooth muscle.

Vasodilation plays an important role in the management of various cardiovascular conditions, as it can help reduce blood pressure and improve blood flow. The dual mechanism of action seen with phenothiazines is particularly useful in clinical settings where both sedation and cardiovascular stabilization may be necessary.

The other options listed do not exhibit the same combination of effects. For example, Xylocaine (lidocaine) primarily functions as a local anesthetic and has antiarrhythmic properties but does not have significant vasodilatory effects through adrenergic receptor interactions. Digoxin is a cardiac glycoside that primarily affects cardiac contractility and heart rate, without direct vasodilatory action through adrenergic receptors. Timolol is a non-selective beta-adrenergic antagonist used mainly to treat glaucoma and hypertension but does