What is the primary function of plasmin in the blood?

Plasmin's primary function in the blood is to break down fibrin, which is a key component of blood clots. Plasmin is an enzyme that is formed from its precursor, plasminogen, through the action of various activators, such as tissue plasminogen activator (tPA). Once activated, plasmin cleaves fibrin, leading to the dissolution of clots in a process known as fibrinolysis. This process is crucial for the maintenance of hemostatic balance, allowing the body to prevent excessive clotting while also facilitating tissue repair and healing after a vascular injury.

Understanding the role of plasmin is essential in the context of cardiovascular perfusion and patient management during surgical procedures, as it helps to control clot formation and dissolution, impacting both bleeding and thrombotic complications.