What is NOT a result of the complement split product C5a?

The complement split product C5a is known for several significant roles in the immune response, primarily as a potent inflammatory mediator. It is primarily associated with enhancing inflammation and recruiting immune cells to sites of infection or injury.

C5a is a powerful anaphylatoxin, which means it can trigger mast cell degranulation. When mast cells degranulate, they release various mediators such as histamine and cytokines, contributing to the inflammatory response. This ties into the first choice regarding mast cell degranulation.

Additionally, C5a plays a crucial role in chemotaxis, particularly for neutrophils. It attracts these immune cells to the site of infection or inflammation, facilitating the body’s defense mechanisms. This is accurately reflected in the second choice focusing on neutrophil chemotaxis.

Moreover, C5a is involved in lysosomal enzyme release, as it stimulates the activity of neutrophils and other immune cells to degranulate and release enzymes that can help combat pathogens. This aligns with the third option related to lysosomal enzyme release.

In contrast, the option regarding membrane lysis is not a direct action of C5a. Membrane lysis is typically associated with the terminal pathway of complement activation, which involves the