Indications for FFP transfusion include all of the following EXCEPT:

Fresh Frozen Plasma (FFP) is a blood product that contains clotting factors and is used in various clinical scenarios to manage coagulopathies and bleeding. Each of the indications for FFP transfusion pertains to specific clinical situations where the replenishment of clotting factors is critical.

The first option correctly indicates that patients who are bleeding or are prepared for surgery and have multiple coagulation protein deficiencies would benefit from FFP. FFP not only replaces these deficient factors but also helps to restore the normal coagulation pathway.

The second option highlights the role of FFP in the rapid reversal of the anticoagulant effects of Coumadin. In cases of severe bleeding or urgent surgical procedures, FFP can be used to quickly restore vitamin K-dependent factors (II, VII, IX, and X), which are often affected by Coumadin therapy.

The third option refers to Von Willebrand deficiency but is phrased in a way that is misleading. While FFP can be helpful in managing bleeding in patients with Von Willebrand disease, it is not typically considered a frontline treatment, especially in cases that are refractory to heparin. Generally, patients with Von Willebrand disease may require more specific treatments like desmopressin or Von Willebrand