Which benefit has been suggested for pulsatile perfusion?

Pulsatile perfusion has been suggested to have several potential benefits, one of which is the improvement of kidney function. This is particularly important during cardiac surgery and in patients who may develop acute kidney injury. Pulsatile perfusion mimics the natural rhythm of the heart, which may enhance renal perfusion and promote more effective filtration and excretion of waste products by the kidneys.

The kidneys are highly dependent on adequate blood flow for proper function. Studies have indicated that continuous flow during cardiopulmonary bypass can lead to renal hypoperfusion, whereas pulsatile flow can help maintain better hemodynamic conditions, ensuring that the renal vasculature receives sufficient blood supply. This improved blood flow can help reduce the risk of acute kidney injury and enhance overall kidney function during and after surgical procedures.

While other potential benefits associated with pulsatile perfusion may exist, such as effects on total peripheral resistance or arterial blood pressure, the specific enhancement of kidney function is a significant aspect that underscores the importance of using pulsatile strategies in perfusion practices. This factor is critical for perfusionists to consider when evaluating their perfusion approach in clinical settings.